S1P -> GPCR_ Apoptosis_ -| GPCR_ Apoptosis_ -| SMAD_ GPCR_ -> SMAD_ Apoptosis_ -| TCR CTLA4_ -| TCR Apoptosis_ -| MCL1 DISC_ -| MCL1 Apoptosis_ -| IAP_ BID_ -| IAP_ Apoptosis_ -> Apoptosis_ Caspase -> Apoptosis_ Apoptosis_ -| DISC_ Fas -> DISC_ FLIP_ -| DISC_ Ceramide_ -> DISC_ Apoptosis_ -| FLIP_ DISC_ -| FLIP_ Apoptosis_ -| S1P Ceramide_ -| S1P Apoptosis_ -| P2 IFNG_ -> P2 P2 -> P2 S1P -> sFas Apoptosis_ -| sFas Apoptosis_ -| IFNG_ SMAD_ -| IFNG_ P2 -| IFNG_ Apoptosis_ -| CTLA4_ TCR -> CTLA4_ Apoptosis_ -| Fas sFas -| Fas S1P -| Ceramide_ Apoptosis_ -| Ceramide_ Fas -> Ceramide_ MCL1 -| BID_ Apoptosis_ -| BID_ IAP_ -| Caspase Apoptosis_ -| Caspase BID_ -> Caspase DISC_ -> Caspase Apoptosis_ -| CREB IFNG_ -> CREB $Apoptosis_: (Apoptosis_ | Caspase) $BID_: !(Apoptosis_ | MCL1) $CREB: (IFNG_ & !Apoptosis_) $CTLA4_: (TCR & !Apoptosis_) $Caspase: ((DISC_ & !Apoptosis_) | (BID_ & !(Apoptosis_ | IAP_))) $Ceramide_: (Fas & !(S1P | Apoptosis_)) $DISC_: ((Ceramide_ & !Apoptosis_) | (Fas & !(Apoptosis_ | FLIP_))) $FLIP_: !(Apoptosis_ | DISC_) $Fas: !(sFas | Apoptosis_) $GPCR_: (S1P & !Apoptosis_) $IAP_: !(BID_ | Apoptosis_) $IFNG_: !((Apoptosis_ | P2) | SMAD_) $MCL1: !(Apoptosis_ | DISC_) $P2: ((IFNG_ & !Apoptosis_) | (P2 & !Apoptosis_)) $S1P: !(Apoptosis_ | Ceramide_) $SMAD_: (GPCR_ & !Apoptosis_) $TCR: !(Apoptosis_ | CTLA4_) $sFas: (S1P & !Apoptosis_)